An overview of dimensionality reduction techniques

Let's learn about some of the dimensionality reduction techniques that feature prominently in neuroscience literature.

Your Goal

This activity is not about getting every question right. It's about exploring the impact each technique would have on a project, and how different techniques can empower or mislead researchers—you are not expected to know the techniques featured, and this will not teach you how to implement them on a technical level.

Techniques You'll Encounter

Principal Component Analysis (PCA)

Often used for fMRI pattern analysis & variance-based feature extraction

Independent Component Analysis (ICA)

Common for EEG/MEG source separation and/or artifact removal

Linear Discriminant Analysis (LDA)

Commonly used to decode labeled states in neural data.

Uniform Manifold Approximation and Projection (UMAP)

Often used in studies featuring scRNA-seq and/or complex population activity

Non-negative Matrix Factorization (NMF)

Commonly used in calcium-imaging analysis and fMRI brain mapping

Over the next few screens, you'll be presented with various research scenarios that each feature a question in need of an answer. You are tasked with picking a dimensionality reduction technique that might answer that question.

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